PRP Therapy in Tokyo (Cellular Matrix PRP+HA)

PRP (platelet-rich plasma) is prepared from a small sample of your own blood. The blood is centrifuged to separate the platelet-rich fraction, which contains growth factors that signal your fibroblasts to produce new collagen and elastin. When injected into the skin, PRP restores firmness and natural volume gradually, without the defined edges that a filler can leave.

The result depends on the preparation kit. Many kits concentrate platelets only two to three times. Rejuva uses a high-performance kit that concentrates platelets more than eight times with a platelet recovery rate above 80%, so that each session delivers a stronger signal for tissue regeneration.

At Rejuva, PRP is prepared as Cellular Matrix, which combines the PRP with non-crosslinked hyaluronic acid. The hyaluronic acid is not a filler: it is not crosslinked, so it does not add lasting volume. Instead, it acts as a scaffold that holds the growth factors at the injection site and provides hydration that PRP alone does not.

Cellular Matrix is priced the same as the clinic's standard PRP treatment. Dr. Hirata explains the differences from PRP alone, why hyaluronic acid is added, and what the clinical evidence does and does not show in her article PRP + Non-Crosslinked Hyaluronic Acid: What Is Cellular Matrix?.

• Face: nasolabial folds, under-eye hollows, fine lines, and overall skin firmness. The full-face price is quoted at the consultation and is equivalent to hyaluronic acid fillers.
• Scalp: PRP injected into the scalp stimulates new capillaries around weakened follicles, for thinning hair in both men and women.
• Intimate area: injection into the vaginal wall or labia majora for laxity, atrophy, and dryness after childbirth or with age; injection into the clitoris or G-spot for reduced sensitivity.

Three doctors, including clinic director Dr. Rena Hirata, offer consultations in English. No interpreter is needed, and English-speaking patients pay the same prices as Japanese-speaking patients. The treatment takes about 60 minutes including the blood draw and preparation. Mild swelling and redness usually settle within one week, so most visitors can continue sightseeing or travel the next day.

A course of three sessions is recommended. If you are visiting Tokyo only once, the doctor will discuss what a single session can and cannot achieve at the consultation.

Prices in Japanese yen, tax included. The initial consultation fee is ¥3,300, including tax. Three sessions are recommended. See the full price list.

Mild to moderate swelling and redness can occur after injection and usually settle within a few days to one week; some patients feel puffiness for two to three weeks. Bruising, when it occurs, is absorbed within one to two weeks. Rarely, firm nodules can form from excess cell proliferation. Because the treatment uses your own blood, allergic reactions are very unlikely, but infection remains a rare possibility. Please tell the doctor about any medical conditions, medications, or allergies at the consultation.

PRP therapy at Rejuva is provided under a Class III regenerative medicine plan filed with the Ministry of Health, Labour and Welfare (plan number PC3200161), as required by Japan's Act on the Safety of Regenerative Medicine.

Cellular Matrix (a preparation kit that combines PRP with non-crosslinked hyaluronic acid) has not been approved under Japan's Pharmaceuticals and Medical Devices Act. The clinic imports it through an authorized Japanese distributor at the physician's discretion. No product with equivalent indications has been approved in Japan, and safety certification in other countries has not been confirmed. No serious adverse events have been reported to date, but risks that are not yet known may exist. Serious adverse events arising from this treatment are not covered by Japan's Relief System for Sufferers from Adverse Drug Reactions. Information on personally imported medical products: yakubutsu.mhlw.go.jp.